Harry and Anastasia are expecting their first child, but there are forces in the world that do not and never will accept Harry's kind. Transgenics frighten people, and in a bid to win over public opinion, Harry puts his best foot forward.

However, other forces are at work. Allenby, a mad scientist, is still alive and out to reshape humanity to his whims. Government officials also stand in the way of societal acceptance.

Added into the mix are the arrival of some new transgenic creations, and Harry is forced once again to take them on with the help of Pavel, a Russian dog-demon, and bring the fight to one of the coldest regions in Russia. For his wife's sake as well as his daughter's sake, this is one fight Harry intends to win.